Rashford put United back on top just before the break after a quick one-two with Hojlund for his fourth goal of the season and first at home.
Bentancur cancelled out Rashford’s goal when he scored less than a minute after the interval, taking a pass from debutant Timo Werner before firing the ball past goalkeeper Andre Onana.
“To play for a new club in this stadium against United, you’re always a bit nervous. You try to enjoy it,” Werner, who joined Spurs on loan from RB Leipzig earlier in the week, told Sky Sports.
Scott McTominay almost netted a winner seconds before the final whistle, but his header from Alejandro Garnacho’s pinpoint cross sailed just over the bar.
United were able to delay keeper Onana’s travel to the Africa Cup of Nations so he could play on Sunday. The Cameroonian was scheduled to depart for the Ivory Coast on a private plane right after the match.
Some good news for injury-plagued United was the return of Lisandro Martinez, who played for the first time since their Champions League game against Bayern Munich on Sept. 20.
“Senior players like Casemiro (who was on the bench on Sunday), Martinez and Luke Shaw are returning and when you add that to our team I am sure it is a strong side,” Ten Hag said.
British billionaire Jim Ratcliffe, who struck a deal to take a minority stake at Manchester United last month, attended the game and was spotted talking to United’s former manager Alex Ferguson, who was seated next to him.